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Aprepitant: Benefits, Reviews, Info, Side Effects!
Rx Details
Aprepitant
Emend, Fosaprepitant
Aprepitant
Prescription
Antiemetic
Drugs
Prescription Only
prevention of nausea, prevention of vomiting, used in chemotherapy, used in postoperative recovery, reduces substance P activity, enhances quality of life during treatment
Constipation, Dehydration, Diarrhea, Dizziness, Fatigue, Fever, Headache, Heartburn, Hiccups, Loss Of Appetite, Nausea, Rash, Stomach Pain, Weakness
Aprepitant is typically used to prevent nausea and vomiting caused by chemotherapy. The dosage can vary based on the specific treatment regimen, but a common dosing schedule for adults is: – 125 mg orally 1 hour before chemotherapy on Day 1 – 80 mg once daily in the morning on Days 2 and 3 It’s important to note that the exact dosage and schedule may vary depending on the specific chemotherapy regimen and patient needs. Always follow the prescribing doctor’s instructions or the guidelines provided with the medication.
Nausea, vomiting, chemotherapy-induced nausea and vomiting, postoperative nausea and vomiting
Generally well-tolerated, with common side effects including fatigue, constipation, and hiccups.
Warfarin, dexamethasone, cyclosporine, sirolimus, tacrolimus, pimozide, quinidine, vinblastine, irinotecan, atorvastatin, simvastatin, rifampin, ketoconazole, itraconazole, clarithromycin, ritonavir, nelfinavir, saquinavir, indinavir, nefazodone, carbamazepine, phenytoin, phenobarbital, St John’s Wort, midazolam, triazolam, digoxin, metoprolol, warfarin, oral contraceptives, cyclosporine, tacrolimus, sirolimus, pimozide, quinidine, vinblastine, irinotecan, atorvastatin, simvastatin, rifampin, ketoconazole, itraconazole, clarithromycin, ritonavir, nelfinavir, saquinavir, indinavir, nefazodone, carbamazepine, phenytoin, phenobarbital, St John’s Wort, midazolam, triazolam, digoxin, metoprolol
$50 – $150
$1,200

A Synopsis of

Aprepitant

Aprepitant is a medication commonly used to prevent nausea and vomiting caused by chemotherapy. It belongs to a class of drugs known as neurokinin-1 receptor antagonists, which work by blocking the action of a substance in the brain called substance P. Substance P is involved in triggering the vomiting reflex, so by blocking its action, aprepitant helps to prevent chemotherapy-induced nausea and vomiting.

This medication is typically taken in combination with other anti-nausea medications to provide comprehensive relief for patients undergoing chemotherapy. It is available in both oral and intravenous forms, making it convenient for patients to take as prescribed by their healthcare provider.

It is important to follow your healthcare provider’s instructions carefully when taking aprepitant. This medication may interact with certain other medications, so be sure to inform your healthcare provider of all the medications you are currently taking before starting aprepitant.

Common side effects of aprepitant may include fatigue, dizziness, constipation, and changes in taste. If you experience any severe or persistent side effects while taking this medication, be sure to contact your healthcare provider right away.

Overall, aprepitant is a valuable medication for patients undergoing chemotherapy who are at risk for experiencing nausea and vomiting. By working to prevent these side effects, aprepitant can help improve the quality of life for patients undergoing cancer treatment. If you have any questions or concerns about aprepitant, be sure to discuss them with your healthcare provider.

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