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Cladribine: Benefits, Reviews, Info, Side Effects!
Rx Details
Cladribine
Leustatin, Mavenclad, 2-chlorodeoxyadenosine
2-chloro-2′-deoxyadenosine
Prescription
Drug
Drugs
Prescription Only
treatment of relapsing forms of multiple sclerosis, reduction in frequency of clinical exacerbations, slowing progression of disability, oral administration, short treatment courses, potential for long-term remission
Anemia, Back Pain, Cough, Diarrhea, Dizziness, Fatigue, Fever, Hair Loss, Headache, Infections, Insomnia, Joint Pain, Liver Enzyme Elevation, Lymphopenia, Nausea, Neutropenia, Rash, Thrombocytopenia
Cladribine is a medication used primarily to treat certain types of leukemia and multiple sclerosis. The dosage of cladribine can vary depending on the condition being treated, the formulation of the drug, and individual patient factors. Here are some general guidelines: 1. **For Hairy Cell Leukemia:** – Cladribine is often administered as a single course of treatment. – The typical dosage is 0.09 mg/kg/day given as a continuous intravenous infusion for 7 days. 2. **For Multiple Sclerosis (under the brand name Mavenclad):** – The dosage is based on body weight and is given in two treatment courses over two years. – Each treatment course consists of two treatment weeks, one at the beginning of the first month and one at the beginning of the second month. – The total dose over the two years is typically 3.5 mg/kg body weight. It’s important to note that these are general guidelines and the exact dosage should be determined by a healthcare professional based on individual patient needs and response to treatment. Always consult with a healthcare provider for specific dosing instructions.
Multiple sclerosis, hairy cell leukemia
Safety profile of Cladribine is generally favorable.
No Interactions Reported
$1,000 – $5,000
$6,000 for a 10 mg vial.

A Synopsis of

Cladribine

Cladribine, also known by its brand name Mavenclad, is a medication used in the treatment of certain types of multiple sclerosis (MS). It belongs to a class of drugs known as purine analogues, which work by targeting and destroying certain immune cells that are believed to play a role in the development of MS.

Cladribine is typically prescribed for patients with relapsing forms of MS who have not responded well to other treatments. It is taken orally in the form of tablets, making it a convenient option for many patients. The medication is usually given in two treatment courses, one year apart, with each course consisting of two treatment weeks. This dosing schedule helps to reduce the frequency of relapses and slow the progression of disability in patients with MS.

As with any medication, there are potential side effects associated with Cladribine. These can include headaches, nausea, fatigue, and an increased risk of infections. It is important for patients to discuss any concerns or side effects with their healthcare provider.

Before starting treatment with Cladribine, patients should inform their healthcare provider of any other medications they are taking, as well as any medical conditions they may have. It is also important for women who are pregnant or planning to become pregnant to discuss the risks and benefits of taking Cladribine with their healthcare provider.

Overall, Cladribine is a valuable treatment option for patients with certain types of MS. It has been shown to be effective in reducing relapses and slowing the progression of disability in many patients. As always, it is important for patients to work closely with their healthcare provider to determine the best treatment plan for their individual needs.

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