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Glycerol Phenylbutyrate: Benefits, Reviews, Info, Side Effects!
Rx Details
Glycerol Phenylbutyrate
Ravicti, HPN-100, Phenylbutyrate, Sodium phenylbutyrate
Sodium phenylbutyrate
Prescription
Medication
Drugs
Prescription Only
treatment of urea cycle disorders, reduction of ammonia levels, management of hyperammonemia, improved nitrogen excretion, support for liver function
Abdominal Pain, Decreased Appetite, Diarrhea, Dizziness, Fatigue, Headache, Nausea, Vomiting
Glycerol phenylbutyrate is a medication used primarily for the management of urea cycle disorders. The dosage of glycerol phenylbutyrate can vary based on the specific needs of the patient, including their age, weight, and the severity of their condition. Typically, the dosage is individualized and determined by a healthcare professional. For adults and children weighing more than 20 kg, the usual starting dose is often around 5 to 12.4 mL/m²/day, divided into three equally spaced doses. For children weighing less than 20 kg, the starting dose is usually around 0.5 mL/kg/day, also divided into three doses. However, these are general guidelines, and the exact dosage should always be determined by a healthcare provider based on individual patient needs and response to the medication. It’s important to follow the prescribed dosage and consult with a healthcare professional for any adjustments or concerns regarding the medication.
Urea cycle disorders
Generally well-tolerated with mild side effects.
No Interactions Reported
$500 – $1000
$1,200

A Synopsis of

Glycerol Phenylbutyrate

Glycerol phenylbutyrate is a medication that is commonly used to treat urea cycle disorders, a group of rare genetic disorders that affect the body’s ability to break down ammonia. This medication works by helping the body eliminate excess ammonia through the urine, reducing the risk of toxic buildup in the blood.

It is important to follow your healthcare provider’s instructions when taking glycerol phenylbutyrate, as the dosage will vary depending on your individual needs and medical history. It is typically taken orally, either with food or on an empty stomach, and should be swallowed whole with a glass of water.

Like all medications, glycerol phenylbutyrate can cause side effects in some individuals. Common side effects may include nausea, vomiting, diarrhea, and abdominal pain. If you experience any severe or persistent side effects, it is important to contact your healthcare provider immediately.

It is also important to inform your healthcare provider of any other medications or supplements you are taking, as they may interact with glycerol phenylbutyrate. Additionally, women who are pregnant or breastfeeding should consult with their healthcare provider before taking this medication.

Overall, glycerol phenylbutyrate can be an effective treatment option for individuals with urea cycle disorders. By working with your healthcare provider to develop a personalized treatment plan, you can better manage your condition and improve your quality of life.

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