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Leucovorin: Benefits, Reviews, Info, Side Effects!
Rx Details
Leucovorin
Folinic acid, Citrovorum factor, Calcium folinate
Calcium folinate
Prescription
Supplement
Vitamins
Prescription Only
reduced side effects of methotrexate, enhanced effectiveness of fluorouracil, treatment of folate deficiency, rescue therapy in cancer treatment, support for certain anemia types
Allergic Reactions, Diarrhea, Difficulty Breathing, Dizziness, Fatigue, Hives, Itching, Mouth Sores, Nausea, Rash, Stomach Pain, Swelling Of Face/Lips/Tongue/Throat, Vomiting, Weakness
Leucovorin is a medication used to reduce the toxic effects of methotrexate and to enhance the efficacy of fluorouracil in cancer treatment, among other uses. The dosage of leucovorin can vary significantly depending on the specific use case, the patient’s condition, and the protocol being followed. Here are some general guidelines: 1. **Methotrexate Rescue**: When used to reduce the toxic effects of methotrexate, leucovorin is typically administered at a dose of 10 to 15 mg (or more) every 6 hours, starting 24 hours after the beginning of the methotrexate infusion. The duration and exact dosage depend on the methotrexate levels and the patient’s renal function. 2. **Colorectal Cancer (with Fluorouracil)**: When used in combination with fluorouracil for colorectal cancer, leucovorin is often given at a dose of 200 mg/m² to 400 mg/m² intravenously, followed by fluorouracil. 3. **Folic Acid Deficiency**: For folic acid deficiency, leucovorin is sometimes given at a dose of 1 mg to 5 mg per day. It’s important to note that these are general guidelines and the exact dosage should be determined by a healthcare professional based on individual patient needs and treatment protocols. Always consult with a healthcare provider for specific dosing recommendations.
Folate deficiency, methotrexate toxicity, colorectal cancer, megaloblastic anemia, methanol poisoning
Generally well-tolerated with minimal side effects.
Methotrexate, Fluorouracil, Trimethoprim
$20 – $50
$15.00

A Synopsis of

Leucovorin

Leucovorin, also known as folinic acid, is a medication commonly used in conjunction with certain chemotherapy drugs to help reduce the toxic effects on healthy cells. It is a form of folic acid that is easily absorbed by the body and can help to protect healthy cells from the damaging effects of chemotherapy.

Leucovorin works by helping to replenish the body’s supply of folate, which is essential for the production of new cells and DNA. By providing this essential nutrient, Leucovorin can help to support the body’s natural healing processes and reduce the risk of certain side effects associated with chemotherapy, such as mouth sores, nausea, and low blood cell counts.

This medication is typically administered by injection or infusion, and the dosage will vary depending on the specific chemotherapy regimen being used. It is important to follow your healthcare provider’s instructions carefully and to report any side effects or concerns promptly.

While Leucovorin can be a valuable tool in the fight against cancer, it is not without its own risks and side effects. Common side effects may include diarrhea, nausea, vomiting, and allergic reactions. In rare cases, Leucovorin can cause more serious side effects such as low blood cell counts or liver problems.

As with any medication, it is important to discuss the potential risks and benefits of Leucovorin with your healthcare provider before starting treatment. They can help you determine if this medication is right for you and provide guidance on how to manage any side effects that may occur.

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The information provided on RxDB.net is for informational purposes only and is not intended to replace professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare professional, such as a doctor or pharmacist, for any questions or concerns regarding your health, medications, or medical conditions. Reliance on any information provided on this website is solely at your own risk. RxDB.net does not provide medical or pharmaceutical services and is not liable for any decisions made based on the information contained herein.

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